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In the LEADER trial, a total of 9,340 subjects with T2D and high CV risk were randomized to liraglutide or placebo and followed-up for a median of 3.8 years (100)
Patients should stop tirzepatide and seek immediate medical care if they experience severe, persistent abdominal pain (which may indicate pancreatitis), symptoms of gallbladder disease (right upper quadrant pain, fever, jaundice), persistent vomiting leading to dehydration (which may cause acute kidney injury), or signs of severe allergic reaction
There is not enough evidence to say with 100% certainty whether Ipamorelin/CJC 1295 causes acne, as research has not dug deep enough to know their exact involvement in causing acne