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These include: Hypertension or high blood pressure High cholesterol Osteoarthritis Obstructive sleep apnoea Asthma/COPD Non-alcoholic fatty liver disease Polycystic ovarian syndrome Some people may be eligible with a slightly lower BMI, for example those from certain ethnicities including those of Asian, Chinese, Middle Eastern, Black African or African-Caribbean origin

Avoid using Semaglutide with medications that cause hypoglycemia unless under medical supervision

These autoantibodies against immunomodulatory proteins (including cytokines, chemokines, complement components and cell-surface proteins) could attack tissues of patients, thereby impair host cell signals, perturb immune function, damage organ systems, and increase COVID-19 severity 36

It also honors the biology of GLP-1, respects the risks of overtreatment and centers the discussion where it belongs: not on weight but on metabolic function and food addiction, particularly to refined carbohydrates