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"The collective therapeutic potential of cerebral ketone metabolism in traumatic brain injury." Journal of Lipid Research , 55(12)

Over 26 weeks, cagrilintide demonstrated dose-dependent weight loss with the 4.5 mg dose achieving approximately 10.8% reduction compared to 3.0% with placebo

[6] [3] [10] A mild deficiency may not cause any discernible symptoms, but moderate deficiency can cause various symptoms, such as feeling tired, lightheadedness, headaches, cold intolerance, pale skin, sore tongue, upset stomach, loss of appetite, hair and skin color changes, numbness or tingling (pins and needles) of the fingers and toes, and tinnitus, and vision, cognitive or psychological problems

If approved, brepocitinib would be the first targeted therapy approved for dermatomyositis, a rare and debilitating inflammatory muscle disease with no approved targeted treatment