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Symptoms of vitamin B12 deficiency include weakness, anemia, and neurological issues, making regular monitoring through blood tests important for those with ulcerative colitis

Cognitive and psychological problems such as memory loss, confusion, irritability, or depression appear after prolonged deficiency of vitamin B12

Common mild side effects: injection site soreness (1224 hours, resolves without treatment), brief warmth or flushing immediately after injection, occasional acne with regular use

The absence of verified pharmacokinetics and product verification prevents evidence-based recommendations regarding discontinuation timing, perioperative safety, and postoperative resumption, leaving surgeons unable to quantify risk in elective operative settings