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As discussed earlier, Koeth et al.'s study on gut microbiota-induced TMAO in stable patients undergoing cardiac evaluation showed significant dose-dependent associations between plasma L-carnitine levels and risks of coronary artery disease, peripheral artery disease, and overall CVD after correction for common CVD risk factors [18]

This is achieved by decreasing hunger signals in the brain and slowing digestion, which together help you feel fuller with smaller portions and stay satisfied between meals

Research shows that it's possible to lose up to 22.5% of your starting body weight after 72 weeks of treatment on its highest maintenance dose