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Vascular endothelial dysfunction reduces nitric oxide production impairing vasodilation

Laboratory studies demonstrate that senescent cancer cells maintain similar FOXO4-p53 interactions that protect them from apoptosis, making them susceptible to FOXO4-DRI-mediated elimination while providing researchers with tools for studying cancer cell senescence and survival mechanisms

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And frankly, we never will, because no pharmaceutical company is going to spend billions getting FDA approval for a naturally occurring peptide they cant patent for themselves