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Increasing Age and Other Factors Reduce the Bodys Production and Utilization of GSH

Stress management: Chronic stress depletes glutathione, so practices like meditation and yoga can help maintain its levels

In a first part, I discuss biological issues related to the persistence of microbial antigens, dysregulated immune responses, reactivation of latent viruses, different potential self-sustained inflammatory loops, mitochondrial dysfunction, metabolic disorders in the tryptophan- kynurenin pathway (TKP) with impact on serotonin, and consequences of a dysfunctional bidirectional microbiota-gut-brain axis