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doi: 10.1021/acs.jafc.6b03546 411 TianX.ZhangC.QinZ.WangD.YangJ.ZhangX.et al

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(139) confirmed in 2023 that serum BCAA levels can serve as effective indicators of DKD, with BCAA levels beginning to decline in the microalbuminuria stage and further declining in the macroalbuminuria stage, negatively correlated with urinary microalbumin levels and positively correlated with serum albumin levels, indicating that BCAAs are closely related to nutritional status in T2DM patients

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A 2019 study in the Journal of Clinical Endocrinology & Metabolism found that calorie restriction without pharmacological intervention increased plasma lipid peroxidation markers (malondialdehyde) by 18% over 12 weeks in obese adults

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