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Longer term For longer cycles, review weight, symptoms, and metabolic trends every 3-6 months with a clinician

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To further explore the substrate scope of arGSTs, additional yeast systems were engineered using a one-plasmid strategy containing genes encoding dihydroflavonol-4-reductase (DFR), LDOX, a range of arGST and non-arGSTs (as negative controls) and anthocyanidin-3- O -glucosyl transferase (A3GT) (Fig