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Devasagayam TP, et al

MOTS-c (Mitochondrial-Derived Peptide) is a naturally occurring 16-amino acid peptide encoded by the mitochondrial genome (specifically the 12S rRNA gene)

In human pulmonary fibroblast cultures, Epithalon treatment induced telomerase activity in cells that had ceased expressing the enzyme, resulting in telomere elongation and an extension of replicative lifespan beyond the Hayflick limit [1]

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