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Kojic Acid vs Glutathione Benefits Kojic acid works to fade blemishes on the skin's surface, while glutathione lightens the skin from within for an overall glow

Further, biomarker concentrations are tricky to interpret: Total GSH concentration often fails to accurately reflect redox balance, which is better indicated by the GSH to GSSG ratio, plasma/serum concentrations are often a weak correlate of tissue level (the locus of action), and compartmentalization within cells (cytosol versus mitochondria) adds another layer of complexity often out of grasp in clinical samples [31]

C., Howarth, C