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GLOBAL GLUTATHIONE MARKET SIZE, BY OXIDIZED GLUTATHIONE, BY REGION, 2018-2032 (USD MILLION) TABLE 116

Intestinal and brain cells contain prohormone convertase 1 (PC1), which is able to cleave proglucagon into Glicentin, Oxyntomodulin, GLP-1, GLP-2 and IP-2, while pancreatic islet cells contain prohormone convertase 2 (PC2), which capable of cleaving proglucagon into Glucagon and MPGF

Berberine and GLP-1 medications work through different mechanisms and have no direct drug interactions, so combining them is theoretically possible

Moreover, mechanistic interpretations derived from spectroscopic studies of interactions with biomolecules such as DNA or HSA remain largely indirect and require further biochemical validation