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High-dose Vitamin B12 May Improve ALS Prognosis if Started Early, Study Suggests Written by | Treatment with ultra-high-dose methylcobalamin, the physiologically active form of vitamin B12, may improve the prognosis of patients with amyotrophic lateral sclerosis (ALS) who receive it a year or less after symptom onset, a long-term study of Japanese reports

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J Biol Chem 295:1373713752