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hence, treatment guidelines do not recommend these agents in pregnancy. Thus, the lack of data on the safety of second-line noninsulin antidiabetic medications in the prenatal period has been a barrier to their use in pregnant women even when they may be beneficial, particularly for patients that dont need or dont tolerate insulin injections, Dr

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We suggest starting doses using PCCA Naltrexone Hydrochloride USP Anhydrous (PCCA # 50-4377 ), prepared in 0.5 mg capsules with LoxOral (PCCA # 30-4774 ) as the filler, and titrate 0.5 mg every two weeks up to a maximum of 4.5 mg daily