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IbanezBMacayaCSanchez-BruneteVPizarroGFernandez-FrieraLMateosAet alEffect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the effect of metoprolol in cardioprotection during an acute myocardial infarction (METOCARD-CNIC) trial