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The north pole has eight such vortices, arranged in two sets of four like two squares rotated slightly with respect to each other, while the south pole has five in a nearly perfect pentagon

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GLP-1 analogs, such as Liraglutide and Exendin-4, unlike endogenously produced GLP-1, are not rapidly degraded by Dipeptidyl peptidase-4 (DPP-4) and, therefore, can induce sustained therapeutic actions, that otherwise would not be possible due to the exceedingly short half-life of endogenous GLP-1 in circulation