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Patients should contact their GP or diabetes specialist nurse if they experience: New onset or worsening erectile dysfunction after starting tirzepatide Sexual dysfunction accompanied by other concerning symptoms such as chest pain, breathlessness, or leg pain (which may indicate cardiovascular disease) Psychological distress related to sexual function affecting quality of life or relationships Concerns about whether tirzepatide or other medications may be contributing to symptoms During consultation, healthcare professionals will typically conduct a comprehensive assessment including medical history, medication review, cardiovascular risk evaluation, and consideration of psychological factors

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Potential Links to Skin Cancer: There have been reports of the development of dysplastic naevi and melanoma associated with Melanotan use