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Impaired gut barrier function: Gluten or dairy sensitivity can lead to increased intestinal permeability or "leaky gut," which may impair the release of DAO into the intestinal lumen where it is needed to break down histamine

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Clinical trial access depends on study criteria and site screening, while approved medical treatment requires a regulator-authorized product and clinician direction

It targets GI tract inflammation with lower systemic absorption compared to other corticosteroids