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Collectively, these findings emphasize the central role of the VDR signaling axis in constraining aberrant melanocyte proliferation, with its progressive dysfunction potentially serving as a key determinant in the malignant transformation of benign nevi to melanoma
Trends Biochem Sci 21:383387 Liao X, Butow RA (1993) RTG1 and RTG2: Two yeast genes required for a novel path of communication from mitochondria to the nucleus
While ECL2 and ECL3 are relatively conserved within class B receptors 21 , the stalk and ECL1 regions are highly variable between GLP-1R and GCGR (Fig
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