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This pathway not only suppresses CD8T cell infiltration but also downregulates major histocompatibility complex class I (MHC I) expression and inhibits interferon-gamma (IFN-) signaling, thereby undermining antitumor immune responses at multiple levels [85]

Identification of pathways related to enriched metabolites demonstrated vast metabolic upregulation, including glucose, glutamine, serine, and arginine metabolism in pathologies such as pancreatic adenocarcinoma and triple-negative breast cancer (TNBC) 9,10,11

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Copper peptides are naturally occurring complexes that play vital roles in regular tissue repair, vascular endothelial growth factor (VEGF) secretion, and extracellular matrix maintenance