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This pointed to something unexpected: the gut was actively signalling to the pancreas

I have had several doctors and a nutritionist express surprise that I am on Ozempic because 'I am at a normal BMI.' Like duh

In our model of allergen-induced allergic airways disease we noted a strikingly beneficial effect associated with melatonin treatment whereby pulmonary eosinophilia and airway hyperreactivity were significantly reduced

Myostatin (GDF-8), a member of the TGF-beta superfamily, is a negative regulator of muscle mass that signals through SMAD transcription factors and tends to oppose the Akt/mTOR-driven hypertrophic program that IGF-1 promotes