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When traveling, it may help to: Keep medication out of direct sunlight Avoid leaving it in a hot car Use an insulated medication pouch when needed Keep medication in its original packaging Ask your pharmacist about safe travel storage When to Call Your Doctor Contact your healthcare provider if you are taking a GLP-1 medication and experience: Ongoing vomiting or diarrhea Signs of dehydration Fainting or severe dizziness Confusion Very little urination Severe weakness Symptoms that worsen in hot weather Seek emergency care if you or someone nearby has signs of heat stroke, including confusion, loss of consciousness, seizures, or very high body temperature

These were patients with heart disease, overweight or obesity, and metabolic stress driving silent inflammation and atherosclerosis progression

In a Phase 2 trial, people on the highest dose lost 24.2% of body weight at 48 weeks, and 17.5% at 24 weeks

Variants in GLP1R, GIPR, FTO, and MC4R genes influence GLP-1 signaling efficiency and metabolic response