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Patients on any oral antihyperglycemic agent in monotherapy (N=212) or on a PPAR agent in combination therapy (N=106) or not on an antihyperglycemic agent (off therapy for at least 8 weeks, N=34) were switched to monotherapy with pioglitazone (at a dose of 30-45 mg per day), and completed a run-in period of approximately 12 weeks in duration

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The disconnect between the population prevalence of obesity and care utilization is driven by a range of factors such as stigma and discrimination in healthcare settings, lack of educational and cultural training among physicians on how to address this issue with patients, and the cost of treatment

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