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These unit costs were used to calculate annual costs of treatment for each arm, based on the resource use from the PIONEER 2 and 3 clinical trials for comparisons with empagliflozin and dulaglutide, respectively

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Specifically, the activity and transcript abundance of glutathione peroxidases, which convert GSH to GSSG, increased in infested resistant plants, but the enzymatic activity and transcript abundance of glutathione reductases, which converts GSSG back to GSH, did not change