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HFD can metabolic dysfunction-associated steatotic liver disease (MASLD) by increasing the uptake of free fatty acids by hepatocytes, disrupting the balance between de novo synthesis and oxidative degradation of fatty acids, leading to excessive deposition of triglycerides (TG) in hepatocytes

In mammals, the OR gene family is one of the largest GPCR families, with approximately 370 genes in humans ( 3.2 Role and general mechanism of olfactory receptors in other systems Beyond the olfactory system, ORs have been detected in various non-olfactory tissues, including the respiratory tract, digestive system, skin, and immune cells ( Generally speaking, how do olfactory receptors function

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