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2 Down syndrome caused by translocation involves a partial duplication of chromosome 21 that is attached to another chromosome

For patients like Maria, who have mild hyperlipidemia, the transdermal route is safer and provides effective symptom control without increasing cardiovascular risk

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For example, a randomized, double-blind, placebo-controlled study of 2,695 stroke survivors with or without cognitive impairments found daily supplementation with 2 mg of folic acid, 0.5 mg of vitamin B 12 , and 25 mg of vitamin B 6 for 3.4 years significantly reduced mean homocysteine levels (by 28% and 43% in cognitively unimpaired and impaired patients, respectively) compared to placebo