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Gut Microbiome Modulation in Diet-Induced Obesity (PubMed, 2022) 5-Amino-1MQ Establishes a Distinct Microbiome Profile in DIO Mice A study published on PubMed investigated the effects of 5-Amino-1MQ combined with a low-fat diet on the gut microbiome of diet-induced obese mice

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Currently, a clinical trial of E6011 (an anti-CX3CL1 mAb) has been demonstrated to have a promising role in active RA patients ( ( Figure 2 )