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205 In conditions of adequate methionine availability, conversion of homocysteine to methionine is suppressed, and an alternate metabolic pathway is engaged to regulate homocysteine levels

A population-average curve obtained by taking the mean , and across diabetic patients (bold curve in Figure 3) reveals quantal characteristics of the average GSH response to glucose: Hyperglycemia is associated with a shallow low-glutathione phase

Similarly, while the previous study 19 showed higher levels of protein C, which is a prothrombinase complex inhibitor, in splenectomized patients as compared to healthy volunteers and non splenctomized patients, our study showed increase activation of the prothrombinase complex as shown by the increased levels of prothrombin fragment 1 + 2 in the splenectomized patients