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Early amylin analog development was marked by pramlintide's modest clinical impact (~23% weight loss) and poor adherence due to three-times-daily dosing

Figure 1: Showed the right mandibular edentulous ridge of a patient diagnosed with CTN and the fabricated stent to cover the painful site Pharmacological methods Pharmacological treatments include antidepressants (e.g., SSRIs, SNRIs, TCAs) and anticonvulsants (e.g., gabapentin, carbamazepine), which suppress neuronal hyperexcitability

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Neck: Slower response