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Incretin based drugs and risk of cholangiocarcinoma among patients with type 2 diabetes: population based cohort study

Any perturbation of this balance, caused by excessive production of disulphide bonds during normal protein secretion or the production of mutant misfolded protein, might cause an excess of ROS to accumulate and ultimately lead to cell death

The concept of osmotic control of the BBB was also based on electron microscope studies, in which it was shown that the nuclei of ECs seemed to have a contracted, raisin-like appearance after exposure to histamine

Transportation of nutrients thoughout the body