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Another activator of the PINK1/Parkin-dependent mitophagy is L-carnitine, which maintains mitochondrial functions and normal state of heart microvessels

HeLHeXLimLPde StanchinaEXuanZLiangYet alA microRNA component of the p53 tumour suppressor network

Individuals with type 1 diabetes, thyroid cancer, multiple endocrine neoplasia, or end stage kidney disease at any time until cohort entry or individuals with dialysis or the latest eGFR 70 years, by males versus females, by insulin use, by atherosclerotic cardiovascular disease (i.e., myocardial infraction, angina, coronary artery disease, coronary revascularization, peripheral artery disease, aortic atherosclerotic disease, or cerebrovascular disease), by renal insufficiency (i.e., chronic kidney disease or the latest eGFR 70 years (HR [95% CI]: 0.95 [0.831.08])

The mean change in HbA1c was not different between the two approaches (WMD 0.08%, 95% CI 1.07 to 1.23)