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These cases have addressed questions including whether the FDA properly followed its own procedures in making shortage determinations, whether the semaglutide salt form (semaglutide sodium) qualifies as the same drug for compounding purposes, and whether the FDA has the authority to restrict compounding of a drug that remains in clinical shortage even if the agency has technically removed it from its list

Furthermore, elevated UA levels are associated with endothelial dysfunction, vascular injury and remodeling, and increased inflammatory responses [128], and the protective effects of UA can be masked when it exceeds a certain level