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Available Strengths Levothyroxine and Synthroid are available in the following strengths: 25 mcg 50 mcg 75 mcg 88 mcg 100 mcg 112 mcg 125 mcg 137 mcg 150 mcg 175 mcg 200 mcg 300 mcg Side Effects Side effects of levothyroxine may resemble symptoms of hyperthyroidism: Irregular heartbeat Chest pain or shortness of breath Muscle weakness Headache, irritability, or insomnia Hives or rash Tremors Appetite changes or weight loss Diarrhea or vomiting Sensitivity to heat, sweating, or fever Changes in menstrual cycles Hair loss (usually temporary) Serious Side Effects Heart failure symptoms: fatigue, swelling, shortness of breath Heart attack symptoms: chest pain, dizziness, cold sweats Severe allergic reactions: hives, facial swelling, breathing issues Note: This is not a complete list