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Electrolytes: one of the fundamental causes of a hangover is dehydration (and accompanying electrolyte loss), which is why electrolyte supplementation can be such an effective hangover cure 21

Acta Neurobiol Exp (Wars) 79:133147 Erfani S, Moghimi A, Aboutaleb N, Khaksari M (2019) Protective effects of Nesfatin-1 peptide on cerebral ischemia reperfusion injury via inhibition of neuronal cell death and enhancement of antioxidant defenses

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This can lead to fermentation, gas, and irritation of the intestinal lining, which many people experience as bloating or cramping