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(More information) Despite promising initial results, nicotinamide administration has failed to prevent or delay the onset of type 1 diabetes mellitus in high-risk relatives of type 1 diabetic patients

Collectively, animal and human studies investigating dietary choline supplementation emphasize the idea of divergent effects based on the choline source, the subjects genetic and physiological characteristics, and the tissue or cell type studied, suggesting that a more context-specific selection of choline forms may lead to greater health benefits