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Myeloid Trem2 in pro-inflammatory macrophages activates ras-related C3 botulinum toxin substrate 1 (Rac1) through the cyclooxygenase 2/prostaglandin E2 (COX2/PGE2) pathway, promoting the phagocytosis of apoptotic cells accumulated following hepatic ischemia-reperfusion injury in mice, and facilitating macrophage efferocytosis to suppress inflammation (Kwon et al., 2024
They reduce mitochondrial oxidative damage by restricting mitochondrial ROS generation and increasing mitochondrial antioxidant systems such as mitochondrial SOD
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Symptoms of biceps tendon tears or ruptures Biceps tendon tears can be partial or completea complete tear actually separates the tendon into two pieces
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