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Without sufficient B12, this sheath can weaken, which may explain symptoms such as tingling, numbness, memory issues, or brain fog. From an energy standpoint, B12 supports the methylation cycle , a chemical pathway involved in energy metabolism and detoxification

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Distinguished Professor Emeritus Department of Nutrition and School of Medicine University of California, Davis Copyright 2000-2026 Linus Pauling Institute Figure Alternative Text Figure 1