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Goel S, Singh R, Singh V et al (2022) Metformin: activation of 5 AMP-activated protein kinase and its emerging potential beyond anti-hyperglycemic action

This is important because shifts in fat distribution and in body composition that occur during the menopausal transition are associated with increased cardiometabolic risk factors, including elevated blood pressure, elevated low-density lipoprotein, and obesity

This was also confirmed by the high expression of CPT1 mRNA in the liver and muscle of the L-carnitine-fed zebrafish, and the comparable mRNA expressions of ACO in both tissues between the groups

Third, potency assays rarely extend beyond surface immunophenotyping