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Di Minno MND, Pezzullo S, Palmieri V, Coppola A, DAngelo A, Sampietro F, Cavalca V, Tremoli E, Di Minno G (2011) Genotype-independent in vivo oxidative stress following a methionine loading test: maximal platelet activation in subjects with early-onset thrombosis

The drug enhances insulin secretion in a glucose-dependent manner, meaning it stimulates insulin release only when blood glucose levels are elevated, thereby reducing the risk of hypoglycemia

While the 2.5 mg dose is intended as a starter dose, some individuals are super-responders who see consistent results at this level

Not absent, which would be concerning, but manageable