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Beyond its traditional use in managing type 2 diabetes by improving insulin sensitivity, in fact, metformin holds the potential to modulate immune responses through the activation of AMP-activated protein kinase (AMPK) and inhibition of the mTOR pathway (Chen et al., 2022)

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Reason 2: Damaged skin barrier If your skin barrier was already compromised (from overuse of actives, harsh cleansers, environmental damage), copper peptides penetrate too deeply too quickly, causing inflammation rather than beneficial cellular activity