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They are involved in the signaling of various cytokine receptors and are key components of the JAK-STAT(signal transducer and activator of transcription) pathway

Cell 185:881-895 e820 Sumbalova Z, Kucharska J, Rausova Z, Palacka P, Kovalcikova E, Takacsova T, Mojto V, Navas P, Lopez-Lluch G, Gvozdjakova A (2022) Reduced platelet mitochondrial respiration and oxidative phosphorylation in patients with post Covid-19 syndrome are regenerated after SPA rehabilitation and targeted ubiquinol therapy

Propionate exhibits metabolic dualityenhancing the metabolic shift toward glucose utilization for improved energy efficiency while potentially inducing oxidative stress and arrhythmias (e.g., prolonged QT interval) via inhibition of the tricarboxylic acid cycle

PubMed Tkalcevic, V.I., Cuzic, S., Brajsa, K., Mildner, B., Bokulic, A., Situm, K., Perovic, D., Glojnaric, I., Parnham, M.J