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The potentiation was not blocked by the ghrelin receptor antagonist GHRP-6, implying that the mechanism by which GHRP-2 augments morphine-induced analgesia may not depend on ghrelin receptor activation, even though GHRP-2s own analgesic effects do [1]

Urva S, Coskun T, Loghin C et al (2020) The novel dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 (GLP-1) receptor agonist tirzepatide transiently delays gastric emptying similarly to selective long-acting GLP-1 receptor agonists