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While weight loss is achievable, weight maintenance remains a lifetime challenge ( A new generation of anti-obesity medications (AOMs) has revolutionized the way obesity is treated, enabling most patients to lose 10-20% of their body weight

Wegovy helps individuals with obesity and weight-related medical conditions achieve significant weight loss, averaging 12% of body weight within 18 months and, in some individuals achieving much more substantial weight loss over extended periods

hence, the fraction absorbed ( F ) could not be estimated separately in this model

The rate of gastric emptying is delayed, which may impact the absorption of orally administered drugs