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In vitro, ipamorelin released GH from primary rat pituitary cells with a potency and efficacy closely comparable to GHRP-6 achieving an EC50 of 1.3 0.4 nmol/L and an Emax of 85 5% relative to GHRP-6's 100% reference maximum

Unno, et al., Acute enhancement of non-rapid eye movement sleep in rats after drinking water contaminated with cadmium chloride

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It was discovered 130 years ago in baker's yeast ( Saccharomyces cerevisiae )