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Due to their preclinical testing and lack of comparison with other dual receptor agonists such as tirzepatide, further studies are needed to determine whether the effects of these unimolecular compounds are superior to those of clinically tested drugs

Targeting metabolic dysregulation for fibrosis therapy

In addition, the promotion of the catabolism of some amino acids, such as arginine, tryptophan, and cysteine, by MDSCs impedes activation of T cells [120]