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doi: 10.1172/JCI146353 Summary Keywords GIP, GLP-1, tirzepatide, basal insulin, type 2 diabetes, obesity, body weight, hypoglycemia Citation Lisco G, De Tullio A, Disoteo O, De Geronimo V, Piazzolla G, De Pergola G, Giagulli VA, Jirillo E, Guastamacchia E, Sabb C and Triggiani V (2022) Basal insulin intensification with GLP-1RA and dual GIP and GLP-1RA in patients with uncontrolled type 2 diabetes mellitus: A rapid review of randomized controlled trials and meta-analysis

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However, in certain conditions such as premature birth or kidney failure, carnitine demand may exceed natural synthesis capacity, making it an essential nutrient in these special cases [1]

There were slight, but statistically significant, changes in the mean serum ChE activity of some of the residents of treated structures, but the mean erythrocyte ChE was unchanged