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Other proteins also play important roles in desensitization, including phosphodiesterases, RGS family proteins and A-kinase-anchoring proteins

CHAC1 catalyzes the degradation of GSH into 5-oxoproline and cysteinylglycine

Oxidative stress is the overproduction of highly active molecules, such as ROS, and when liver cells are exposed to certain noxious stimuli, leading to an imbalance between the oxidative and antioxidative systems, liver injury occurs (20)

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