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J Clin Endocrinol Metab 92:229234 Perez-Tilve D, Heppner K, Kirchner H, Lockie SH, Woods SC, Smiley DL, Tschop M, Pfluger P (2011) Ghrelin-induced adiposity is independent of orexigenic effects

Recent experiments indicated a role for GPx4 in tumor angiogenesis by suppressing lipid peroxidation derived from 12/15-lipoxygenase activity or cycloxygenase-2 possibly via modulation of ROS sensitive tyrosine kinase signaling pathways (Heirman et al., 2006

The decision to continue, adjust, or discontinue Ozempic should be made collaboratively, weighing the benefits of improved glycaemic control against the impact of gastrointestinal adverse effects on patient wellbeing

These are molecules characterized by very high reactivity and the ability to damage cellular structures