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Heckman KL, DeCoteau W, Estevez A, Reed KJ, Costanzo W, Sanford D, et al
Strategies to minimize immunogenicity include careful peptide design to maintain similarity to natural sequences, appropriate formulation development, and monitoring for antibody formation during clinical development and post-market surveillance
Many companies manufacture different reconstitution solutions, including bacteriostatic water for injection, in the US
Tumor cells use proteins such as SLC1A5 to transport various amino acids and other nutrients and increase the uptake and predation of nutrients by highly expressing SLC transporters to strengthen their own metabolic reprogramming
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