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Beginning with the CY 2028 reporting period, we estimate the annual burden for all participating HOPDs to be 2,133 hours (0.67 hours 3,200 HOPDs) at a cost of $117,443 (2,133 hours $55.06/hour)

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The volume of each weekly dose depends on the experimental protocol and concentration of the reconstituted solution

Since decreased Parasutterella relative abundance may accompany increased stress 80,81 , the increased Parasutterella relative abundance that occurred in this study following diet switch likely arose from the weight loss-mediated negative energy state